Skip to main content
ACR Convergence 2024 Main banner
Final Program


Schedule at a Glance
Legend
Presentation Icons
CME
CME
Non-CME
Non-CME
In Person
In Person
On Demand
On Demand
Live Stream
Live Stream
Active Learning
Active Learning
Emerging Investigator Awardee
Emerging Investigator Awardee
Back
Scientific Session

Metabolic bone disease
General Topic: Basic Science

16S43: Bone Voyage: Inflammatory Bone Loss and Metabolism

Saturday, November 16, 2024
3:00 PM – 4:30 PM Eastern Time
Location: Room 206
CE: 1.5

CME In Person On Demand

    Moderator(s)

  • Teresa Tarrant, MD

    Duke University
    Durham, North Carolina, United States

    Disclosure(s): Amgen: Grant/Research Support (Ongoing); Chiesi: Advisor or Review Panel Member (Ongoing), Consultant (Ongoing), Grant/Research Support (Ongoing); Department of Justice: Consultant (Ongoing); X4 Pharmaceuticals: Consultant (Ongoing), Grant/Research Support (Ongoing)

  • Baohong Zhao, MD, PhD

    Hospital for Special Surgery
    New York, New York, United States

    Disclosure information not submitted.

Inflammatory bone loss is a signature feature and severe consequence of many inflammatory disorders, including inflammatory arthritis. The underlying mechanisms of bone resorption and metabolism in inflammatory settings are largely unknown. This session will highlight novel discoveries in bone metabolisms and inflammatory bone resorption. Dr. Laura Calvi will discuss the efferocytosis by bone marrow stromal cells and its effects on bone metabolism. Dr. Gabriel Mbalaviele will discuss the key role of inflammasomes in bone resorption. Dr. Jae-Hyuck Shim will discuss the molecular mechanisms of RA joint damage.

Learning Objectives:

  • Comprehend the presence of efferocytosis in bone marrow stromal cells and its effects on bone metabolism
  • Discuss inflammasome function in bone resorption
  • Discuss updated mechanisms of RA joint destruction

Presentations:

  • 3:00 PM – 3:30 PM Eastern Time
    Efferocytosis and Bone Metabolism

    Speaker: Laura Calvi, MD – University of Rochester

  • 3:30 PM – 4:00 PM Eastern Time
    Inflammasomes Regulating Bone Resorption

    Speaker: Gabriel Mbalaviele, PhD – Washington University School of Medicine in St. Louis

  • 4:00 PM – 4:30 PM Eastern Time
    Molecular Mechanisms Underlying Inflammatory Joint Damage

    Speaker: Jae-Hyuck Shim, PhD (he/him/his) – University of Massachusetts Chan Medical School