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  • Saturday, Nov 16th
    10:00 AM – 11:30 AM Eastern Time
    16S15: GRASPing and cGASing at SSc Pathogenesis: Molecular Insights into Centromeres, Genes, and Beyond
    Location: Room 144ABC
    Moderator: Paula Ramos, PhD – Medical University of South Carolina
    Moderator: Brian Skaug, MD,PhD – UTHealth Houston Division of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1.5 hours
  • Saturday, Nov 16th
    10:00 AM – 10:30 AM Eastern Time
    Genetic Insights Into African American Scleroderma: The GRASP Project
    Location: Room 144ABC
    Speaker: Pravitt Gourh, MD – National Institutes of Health
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 11:00 AM Eastern Time
    The Single-Cell Transcriptome Across Time and Autoantibody Subtype in SSc
    Location: Room 144ABC
    Speaker: Kristina Clark, MD, PhD, MRCP – University of Oxford
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    11:00 AM – 11:30 AM Eastern Time
    Centromeres and cGAS/STING Pathway in SSc Pathogenesis
    Location: Room 144ABC
    Speaker: Rafael Contreras-Galindo, PhD – University of Alabama at Birmingham
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 11:30 AM Eastern Time
    16S18: Into the Weeds: Bringing the Science of Cannabis to the Rheumatology Patient
    Location: Room 150AB
    Moderator: Dana DiRenzo, MD;RhMSUS;MHS – University of Pennsylvania
    Moderator: Kaleb Michaud, PhD (he/him/his) – University of Nebraska Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Saturday, Nov 16th
    10:30 AM – 11:00 AM Eastern Time
    The Science of Medical Cannabis for Management of Chronic Pain in Rheumatic Diseases
    Location: Room 150AB
    Speaker: Daniel Clauw, MD – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    11:00 AM – 11:30 AM Eastern Time
    Bridging the Pain Gap: Applications of Medical Cannabis in Rheumatology Clinic
    Location: Room 150AB
    Speaker: Bharat Kumar, MD;RhMSUS;MMed – University of Iowa Hospitals and Clinics
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    Systemic Sclerosis & Related Disorders – Clinical Poster I
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0677: Patterns of Raynaud’s Phenomenon Management in Patients with Systemic Sclerosis: A Real-World Data from Community-Based Practices in the United States
    Abstract Poster Presenter: Gulsen Ozen, MD (she/her/hers) – University of Iowa Health Care
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0678: Patients with Interstitial Lung Disease Due to Systemic Sclerosis or Rheumatoid Arthritis Need Monitoring More Frequently Than Annually
    Abstract Poster Presenter: Oliver Distler, MD – Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0679: Comparing Raynaud’s Phenomenon Measurement Tools: Results of the Optimizing Raynaud Phenomenon Outcome Measures in Systemic Sclerosis (ROSS) Study
    Abstract Poster Presenter: Rachel Wallwork, MD, MHS (she/her/hers) – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0680: Clinical Correlates of Physical and Mental Health in Early Systemic Sclerosis: Data from the Collaborative National Quality and Efficacy (CONQUER) Registry
    Abstract Poster Presenter: Ashima Makol, MD (she/her/hers) – Mayo Clinic, Rochester, MN
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0681: Influence of Occupational Exposure to Pollutants on Clinical and Serological Phenotypes in Systemic Sclerosis
    Abstract Poster Presenter: Irene Carrión-Barberà, MD – Hospital del Mar
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0682: Results from Outcomes Selection and Development of a Patient-reported Outcome Measure for a Combined Response Index for Limited Cutaneous SSc: The CRISTAL Project
    Abstract Poster Presenter: Alain Lescoat, MD, PhD – CHU Rennes - University Rennes
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0683: Prognostic Value of Systemic Sclerosis-associated Primary Heart Involvement
    Abstract Poster Presenter: Carina Mihai, MD, PhD – University Hospital Zurich, University of Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0684: The Diagnostic Accuracy of Ultrasound for Low Muscle Mass in Women with Systemic Sclerosis
    Abstract Poster Presenter: Ricardo Xavier, MD, PhD – Universidade Federal do Rio Grande do Sul
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0685: KL-6 and IL-18 Biomarkers in Systemic Sclerosis-associated Interstitial Lung Disease: Enhancing Prognostic Insights into Early Detection, Progression, Lung Volume Changes,and Mortality Risk
    Abstract Poster Presenter: Cristiana Sieiro Santos, MD – Complejo Asistencial Universitario de León
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0686: The Role of Inflammation in Systemic Sclerosis: CRP-Associated Phenotypes and Prognostic Implications
    Abstract Poster Presenter: Cristiana Sieiro Santos, MD – Complejo Asistencial Universitario de León
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0687: Patterns of Disease Progression in Early Systemic Sclerosis Patients with Interstitial Lung Disease
    Abstract Poster Presenter: Lorenzo Beretta, MD – Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0688: Mycophenolate Mofetil Treatment in Limited Cutaneous Systemic Sclerosis Reduces the Risk of Vascular Complication Leading to Treatment Escalation: Emulation of a Target Trial Using Time-dependent Propensity Score-matching
    Abstract Poster Presenter: Enrico De Lorenzis, MD;PhD – Catholic University of the Sacred Heart
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0689: Arrhythmic Burden, Myocardial Markers, and Long-term Survival in Distinct Cardiac Magnetic Resonance Subsets of Systemic Sclerosis
    Abstract Poster Presenter: Enrico De Lorenzis, MD;PhD – Catholic University of the Sacred Heart
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0690: Can Immunosuppression or Vasodilation Prevent the Onset of Interstitial Lung Disease in Systemic Sclerosis? An Association Analysis from the EUSTAR Database
    Abstract Poster Presenter: Cosimo Bruni, MD,PhD – University of Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0691: Predictors of Response and Long-term Efficacy and Safety of Nintedanib in Systemic Sclerosis-Interstitial Lung Disease: Data from an Italian Multicentre Study
    Abstract Poster Presenter: Corrado Campochiaro, MD – IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0692: Evaluation of the New Criteria for Progressive Pulmonary Fibrosis in Patients with Systemic Sclerosis
    Abstract Poster Presenter: Miriam Retuerto Guerrero, MD (she/her/hers) – Complejo Asistencial Universitario de León
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0693: Behind the Bronchiectasis in Systemic Sclerosis. Prevalence and Risk Factors
    Abstract Poster Presenter: Miriam Retuerto Guerrero, MD (she/her/hers) – Complejo Asistencial Universitario de León
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0694: A Unified Vascular Phenotype Score Identifies Systemic Sclerosis Endotypes and Predicts Prognostic Outcomes: Results from the EUSTAR Database
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0695: Prognostic Value of Serum Type I Interferon in Predicting Morbi-Mortality Outcomes in Systemic Sclerosis: Insights from the STRIKE Basket Cohort
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0696: MRI DAVIX Index Is an Imaging Biomarker for Endothelial Damage of Systemic Sclerosis Digital Ulcers
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0697: Association of ANCA-Associated Vasculitis and Development of SSc and SSc-Associated Antibodies: Impact of Pulmonary Arterial Hypertension
    Abstract Poster Presenter: Brett Dinner, MD – Creighton University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0698: Association of Systemic Sclerosis with ANCA-Associated Vasculitis and Large Vessel Vasculitis: Impact of Pulmonary Arterial Hypertension
    Abstract Poster Presenter: Brett Dinner, MD – Creighton University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0700: Prospective Evaluation of Capillaroscopy in Healthy Children
    Abstract Poster Presenter: Tessa Du Four, MD – University Hospital Ghent
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0701: Diagnostic Performances of Vascular Biomarkers Soluble Fms-like Tyrosine Kinase (sFlt-1) and Placental Growth Factor (PlGF) in Scleroderma Renal Crisis: A Case Control Study
    Abstract Poster Presenter: Aïcha Kante, MD, MSc – Université Paris Cité
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0702: AISA 021, a Novel Calcium Channel Antagonist in Development for Raynaud's & Systemic Sclerosis, Has Antagonistic Activity at Sodium Channel Targets for Pain Relief and Treats Scleroderma Pain Better Than Current Calcium Channel Blockers in a Phase 2A Study
    Abstract Poster Presenter: Andrew Sternlicht, MD, MA (he/him/his) – Tufts University Medical Center and Aisa Pharma, Inc.
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0703: Preliminary Results from the RECONNOITER Trial, a Phase 2 Study of AISA 021 in the Treatment of Secondary Raynaud's, Primarily Due to Systemic Sclerosis
    Abstract Poster Presenter: Andrew Sternlicht, MD, MA (he/him/his) – Tufts University Medical Center and Aisa Pharma, Inc.
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0704: Progression of Global Longitudinal Strain and Identification of Left Ventricular Dysfunction in Systemic Sclerosis Patients
    Abstract Poster Presenter: Jennifer Elise Abdalla, MD,MS – Cleveland Clinic
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0705: Identification of Risk Factors for Incident Cardiomyopathy in Patients with Systemic Sclerosis
    Abstract Poster Presenter: Ji Soo Kim, PhD – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0706: Single Center Prospective Cohort of Systemic Sclerosis Patients Who Are At-Risk for Pulmonary Hypertension
    Abstract Poster Presenter: Carleigh Zahn, DO (she/her/hers) – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0707: Comprehensive Skin Assessment in Systemic Sclerosis Using Spatial Frequency Domain Imaging (SFDI)
    Abstract Poster Presenter: Aarohi Mehendale, MS, BS – Department of Biomedical Engineering, Boston University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0708: Outcomes of Intermittent Intravenous Steroid Use During Infusion Therapy in Systemic Sclerosis
    Abstract Poster Presenter: Adarsh Vangala, MD – University of New Mexico
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0709: Linear Combination of Principal Components Achieves Top Performance in Identifying Rheumatologist-Diagnosed Systemic Sclerosis from Electronic Health Records
    Abstract Poster Presenter: Yiming Luo, MD, MHS – Columbia University Irving Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0710: High S100A4 Levels Associate with Inflammation and Vasculopathy in Systemic Sclerosis
    Abstract Poster Presenter: Adela-Cristina Sarbu, MD – Inselspital, Universitätsklinik Bern
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0711: Molecular Signatures in the Skin as Predictors of Longitudinal Clinical Trajectories in Patients with Systemic Sclerosis
    Abstract Poster Presenter: Natania Field, MD – Northwestern Memorial Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0712: Efficacy of Sacubitril/Valsartan in Patients with Systemic Sclerosis and Heart Failure: A Retrospective Analysis
    Abstract Poster Presenter: Nouran Eshak, MSc, MBBCH – Mayo Clinic Arizona
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    10:30 AM – 12:30 PM Eastern Time
    0713: Anti-muscarinic 3 Antibodies in SSc Associate with a More Significant GI and Extraintestinal Clinical Phenotype
    Abstract Poster Presenter: Naveen Kalavar, MD – McGovern Medical School at UTHSC
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    1:00 PM – 2:00 PM Eastern Time
    16S26: CARE to Test Your Knowledge: Retroperitoneal Fibrosis
    Location: Ballroom A
    Moderator: Brendan Antiochos, MD – Johns Hopkins
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Saturday, Nov 16th
    1:00 PM – 2:00 PM Eastern Time
    CARE: Retroperitoneal Fibrosis
    Location: Ballroom A
    Speaker: John Stone, MD,MPH – Massachusetts General Hospital , Harvard Medical School
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    1:00 PM – 2:30 PM Eastern Time
    16S56: Abstracts: Systemic Sclerosis & Related Disorders – Basic Science
    Location: Room 143ABC
    Abstract Moderator: Michael L. Whitfield, PhD – Geisel School of Medicine at Dartmouth
    Abstract Moderator: Kimberly S. Lakin, MD, MS – Hospital for Special Surgery
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Saturday, Nov 16th
    1:00 PM – 1:15 PM Eastern Time
    0781: An Expanded Cytotoxic CD8 T Cell Population Regulated by CD155-CD226 in SSc-ILD
    Location: Room 143ABC
    Presenting Author: Takanori Sasaki, MD, PhD – Brigham and Women's Hospital and Harvard Medical School
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    1:15 PM – 1:30 PM Eastern Time
    0782: 30-Color Full Spectrum Flow Cytometry Identifies Sex Differences in the Circulating Immune Landscape of Systemic Sclerosis
    Location: Room 143ABC
    Presenting Author: Nikhil Jiwrajka, MD;MS – Hospital of the University of Pennsylvania
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    1:30 PM – 1:45 PM Eastern Time
    0783: Spatial Reconstruction of Interstitial Lung Disease
    Location: Room 143ABC
    Presenting Author: Miles Tran, BA – Brigham and Women's Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    1:45 PM – 2:00 PM Eastern Time
    0784: RUNX1 Is Expressed in a Subpopulation of Dermal Fibroblasts and Is Increased with Systemic Sclerosis Disease Severity
    Location: Room 143ABC
    Presenting Author: Michael L. Whitfield, PhD – Geisel School of Medicine at Dartmouth
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    2:00 PM – 2:15 PM Eastern Time
    0785: Exploring the Link Between Atgl-Dependent Lipolysis and Dermal Fibrosis in Systemic Sclerosis
    Location: Room 143ABC
    Presenting Author: Agrani Dixit, B.A. (she/her/hers) – Yale School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Saturday, Nov 16th
    2:15 PM – 2:30 PM Eastern Time
    0786: First Analyses of Transcriptomic Changes in the Skin of SSc Patients upon CD19-targeting CAR T Cell Therapy
    Location: Room 143ABC
    Presenting Author: Janina Auth, MD (she/her/hers) – University Hospital Erlangen, Medicine 3
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    Systemic Sclerosis & Related Disorders – Basic Science Poster I
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    Systemic Sclerosis & Related Disorders – Clinical Poster II
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0951: A Feedback Loop Involving mtDNA, Platelets and Neutrophil Extracellular Traps Amplifies Inflammation in Systemic Sclerosis
    Abstract Poster Presenter: Ulrich Walker, MD – Basel University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0952: Single Cell RNA-seq of Scleroderma-associated Interstitial Lung Disease Lung Explants Reveals an Active, Cytotoxic Natural Killer Cell Population
    Abstract Poster Presenter: Cristina Padilla, MD, MS (she/her/hers) – University of Pittsburgh Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0953: Establishment of Systemic Sclerosis Associated Pulmonary Arterial Hypertension Specific Endothelial Cells Through iPSCs and Their Functional and Molecular Analyses
    Abstract Poster Presenter: Yuki Kudo, MMSc – Hokkaido U - Rheumatology, Endocrinology and Nephrology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0954: Increased Proliferating Natural Killer Cells Exhibit an Aberrant Pro-Inflammatory Gene Signature in Systemic Sclerosis Patients
    Abstract Poster Presenter: Pietro Bearzi, MD – Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich & Campus Bio-Medico University of Rome
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0955: Inhibition of Interleukin-2-Inducible T Cell Kinase with Soquelitinib Demonstrates Efficacy in Preventing Lung Damage in Murine Models of Systemic Sclerosis
    Abstract Poster Presenter: Yannick Allanore, MD,PhD (he/him/his) – Université Paris Cité
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0956: Secreted Frizzled-Related Protein 2 (sFRP2) Regulates Wnt Signaling to Affect Mesenchymal Transition of Lung Epithelial Cells Participates in Interstitial Lung Disease
    Abstract Poster Presenter: Yinlan Wu, MD (she/her/hers) – West China Hospital of Sichuan University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0957: Increased Collagen Deposition and Altered Immune Cell Profiles Are Present in Early and Late Stage Systemic Sclerosis with Gastrointestinal Involvement
    Abstract Poster Presenter: Laura Much, MSc – Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0958: TCR Motifs Identify Unique Clones in African Americans with Systemic Sclerosis
    Abstract Poster Presenter: Urvashi Kaundal, PhD – National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH)
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0959: Radiomics Non-Invasively Conveys Time-Resolved Molecular Pathway Activity in Experimental Fibrosing Interstitial Lung Disease
    Abstract Poster Presenter: David Lauer, PhD, MSc – University Hospital Bern
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0960: The Esophageal Epithelium in Systemic Sclerosis: Cellular and Molecular Dysregulation Revealed by Single-Cell RNA Sequencing
    Abstract Poster Presenter: Matthew Dapas, PhD – Northwestern University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0961: Multi-omics Study of Systemic Sclerosis Immunoglobulins G Effects on Endothelial Cells: A Distinct Profile in Anti-Topoisomerase I Positive Patients
    Abstract Poster Presenter: Aurélien Chepy, MD (he/him/his) – INFINTE U186 inserm, univeristy of Lille
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0962: Characterizing the Contribution of Myeloid Cells to Limited and Diffuse Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: Parker Jones, BA – Feinberg School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0963: Stratification According to Autoantibody Status in Systemic Sclerosis Reveals Distinct Molecular Signatures
    Abstract Poster Presenter: Cornec Divi, MSc,PharmD – CHRU Brest
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0964: Engaging the PD-1 Pathway Attenuates Inflammation Associated Fibrosis in Systemic Sclerosis Fibroblasts and a Preclinical Mouse Model
    Abstract Poster Presenter: Maithri Aspari, MD (she/her/hers) – Aarhus University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0965: Scleroderma Associated Interstitial Lung Disease Is Characterized by Aberrant Lung Epithelial Remodeling
    Abstract Poster Presenter: Monica Yang, MD – UCSF
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0966: CDDO-Me Attenuates Pro-fibrotic Activation in Macrophages and Fibroblasts in Systemic Sclerosis
    Abstract Poster Presenter: Heetaek Yang, BS – Dartmouth College
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0967: Transcriptional Heterogeneity of Immune Cells in the Esophagus of Systemic Sclerosis Patients: A Comparison of Upper and Lower Esophageal Regions
    Abstract Poster Presenter: Hadijat Makinde, PhD – Northwestern University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0968: Proteomic, Transcriptomic, and Functional Characterization of Circulating Extracellular Vesicles in Progressive Scleroderma Interstitial Lung Disease
    Abstract Poster Presenter: Enrico De Lorenzis, MD;PhD – Catholic University of the Sacred Heart
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0969: Role and Mechanism of the Wnt3a-FZD5 Pathway in Regulating the Transformed Intermediate State of Alveolar Epithelial Cells Involved in Pulmonary Fibrosis in Systemic Sclerosis
    Abstract Poster Presenter: Hang Yu, PhD – zhejiang university
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0970: Deubiquitylase (DUB) BRCC36 Isopeptidase Complex (BRISC) Inhibitors Prevent IFNAR1 Deubiquitination to Restore Natural Type I IFN Response in Autoimmunity
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0971: Ligand-Receptor Analysis Reveals Myeloid-Mediated Pro-Inflammatory Responses and Loss of Mesenchymal Signaling Driven by TNFR1 in Experimental Pulmonary Hypertension
    Abstract Poster Presenter: Gaochan Wang, PhD (he/him/his) – University of Rochester
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0972: Downregulated Fli1 in Scleroderma Myeloid Cells Contributes to Cardiac Fibrosis via a Galectin-3/mTOR Dependent Pathway
    Abstract Poster Presenter: Fatima-Ez-zahrae El Adili, MD – Boston University School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    0973: Mechano-transduction via MRTF-A Pathway Is Required for Cytokine Release by Scleroderma Macrophages
    Abstract Poster Presenter: Sandra Lopez, BSc;MSc – University College London
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1557: Estimation of Cardiovascular Risk in Patients with Systemic Sclerosis – Accuracy of Tools Based on SCORE and Its Modifications Compared to Ultrasound Examination of Subclinical Atherosclerosis
    Abstract Poster Presenter: Sabína Oreská, MD, PhD – Institute of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1558: Mapping in Healthy Subjects Different Body Areas for Dermal Thickness and Skin Hardness by High Frequency Sonography and Durometry
    Abstract Poster Presenter: Elvis Hysa, MD – University of Genoa
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1559: Vectorcardiography for Identification of Systemic Sclerosis Patients at Risk for Pulmonary Hypertension
    Abstract Poster Presenter: Saad Ahmed, MD;MSc – Leiden University Medical Centre
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1560: Changes of Cerebral Structure and Perfusion Vary in Different Subtypes of Systemic Sclerosis: A Brain Magnetic Resonance Imaging Study
    Abstract Poster Presenter: Huilin He, MD – Peking Union Medical College Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1561: Association of Large Vessel Vasculitis and Development of SSc and SSc-Associated Antibodies: Impact of Pulmonary Arterial Hypertension
    Abstract Poster Presenter: Brett Dinner, MD – Creighton University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1562: Autoantibody Associations with Disease Manifestations in Patients with Early Diffuse Cutaneous Systemic Sclerosis: The Prospective Registry of Early Systemic Sclerosis
    Abstract Poster Presenter: Aradhna Agarwal, MD, MPH – Columbia University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1563: Prevalence, Risk Factors and Associations for Osteoporosis in Postmenopausal Women with Scleroderma
    Abstract Poster Presenter: Gayane Matusov, MD – Scripps Green Clinic Internal Medicine Residency
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1564: Incidence of Posttraumatic Stress Disorder Secondary to the Diagnosis of Systemic Sclerosis
    Abstract Poster Presenter: Gregory Pugnet, MD;PhD – Toulouse Rangueil University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1565: Prevalence and Risk Factors of Lower Extremities Arterial Disease in Systemic Sclerosis: Preliminary Data from a Single Centre Multidisciplinary Study
    Abstract Poster Presenter: Maria Grazia Lazzaroni, MD, PhD – ASST Spedali Civili di Brescia
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1566: Comparative Analysis of Clinical Features and Outcomes in Late Onset vs. Early Onset Scleroderma Renal Crisis - A Multicenter Study
    Abstract Poster Presenter: Sumbal Wajid, MBBS, MD – Albany Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1567: Systemic Sclerosis Is Associated with Sub-Clinical Abnormalities in Myocardial Energetics, Perfusion and Increased Fibrosis
    Abstract Poster Presenter: Francesco Delgado, PhD – Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom.
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1568: Distribution of Proteinuria in Scleroderma Renal Crisis: A Multi-Center Study
    Abstract Poster Presenter: Arifa Javed, MBBS (she/her/hers) – Albany Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1569: Scleroderma Renal Crisis – Different Phenotypes and Patient Trajectories
    Abstract Poster Presenter: Alexandra Balbir-Gurman, MD – Rheumatology Institute, Rambam Health Care Campus and The Rappaport Faculty of |Medicine, Technion
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1570: Deconvolution of the Lipidomic Signature of Very Early Diagnosis of Systemic Sclerosis (VEDOSS) and Established Disease: Lipid Biomarker Features That Predict Disease Progression in Skin and Lung
    Abstract Poster Presenter: Sunhwa Kim, PhD – AbbVie
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1571: Growth Differentiation Factor 15 Is a Serum Biomarker and Pathogenic Factor of Progressive Fibrosis in Systemic Sclerosis
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1572: Associations Between the Gut Microbiota, Ultra-Processed Food Intake, and Gastrointestinal Tract Symptoms in Patients with Systemic Sclerosis
    Abstract Poster Presenter: Ju Young (Sally) Lee, BA – David Geffen School of Medicine, UCLA
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1573: Early Scleroderma with Non-Raynaud's Symptoms Prior to Raynaud's Onset Is Associated with Rapid Progression to Diffuse Skin Disease and Joint Contractures
    Abstract Poster Presenter: Brian Skaug, MD,PhD – UTHealth Houston Division of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1574: ­­­Therapeutic Strategy in Patients with Mixed Connective Tissue Disease: A Multicenter Retrospective Study in the French MCTD Cohort
    Abstract Poster Presenter: Kevin Chevalier, MSc – Université Paris Cité
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1575: Anti-U1RNP Antibodies Are Associated with a Distinct Clinical Phenotype and a Worse Survival in Patients with Systemic Sclerosis
    Abstract Poster Presenter: Kevin Chevalier, MSc – Université Paris Cité
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1576: New Patient-Reported Outcome Measures for Early Systemic Sclerosis Using the FDA Guidance on Patient Reported Outcome Measures
    Abstract Poster Presenter: Dinesh Khanna, MD, MSc (he/him/his) – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1577: Elevated Neutrophil Extracellular Traps in Systemic Sclerosis-associated Vasculopathy and Suppression by a Synthetic Prostacyclin Analog
    Abstract Poster Presenter: Ramadan Ali, PhD – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1578: Association of Systemic Sclerosis and Other Systemic Autoimmune Disease Diagnosis with Increasing Anti-RNA Polymerase III Antibodies
    Abstract Poster Presenter: Warren Balaja, MD – University of Kansas Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1579: Exploring the Cardiovascular Complications of Pulmonary Arterial Hypertension in Individuals with Systemic Sclerosis
    Abstract Poster Presenter: Omar Mourad, MD – Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1580: Overt Polyautoimmunity and Its Risk Factors in a Multicenter Cohort of Systemic Sclerosis Patients
    Abstract Poster Presenter: Irene Carrión-Barberà, MD – Hospital del Mar
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1581: Neutrophil-to- lymphocyte Ratio: A Possible Biomarker for Clinical Response After Autologous Hematopoietic Stem Cell Transplantation
    Abstract Poster Presenter: Doron Rimar, MD (he/him/his) – Bnai Zion medical center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1582: Impact of Immunosuppressive Treatment on Development and Survival in Systemic Sclerosis Associated Pulmonary Arterial Hypertension (SSc-PAH)
    Abstract Poster Presenter: Stefano Rodolfi, MD – University College London
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1583: The Association of Weakpositive Anti-RNA Polymerase III Antibodies with the Diagnosis and Complications of Systemic Sclerosis and Other Systemic Autoimmune Diseases
    Abstract Poster Presenter: Mashood Badshah, MD – The University of Kansas Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1584: Efficacy of Tofacitinib in the Treatment of Early Diffuse Cutaneous Systemic Sclerosis: A Clinical Study in Bangladesh
    Abstract Poster Presenter: Md Zahid Amin, FCPS(Medicine), MD(Rheumatology), FACR – Central Police Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1585: Characterization of the Fecal Metabolome in Early Systemic Sclerosis
    Abstract Poster Presenter: Arissa Young, MD – UCLA
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1586: The Relationship Between the Presence, Quantity and Distribution of Cutaneous Telangiectasia and Other Vascular Manifestations of Systemic Sclerosis
    Abstract Poster Presenter: John Pauling, PhD, BSc, FRCP, MBBCH – North Bristol NHS Trust
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1587: Predictors of Body Mass Index in an Early Systemic Sclerosis Cohort
    Abstract Poster Presenter: Ali Ayla, MD – UTHealth Houston Division of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1588: Validation of a Lung Ultrasound Interpretation Criteria for Interstitial Lung Disease Screening in Systemic Sclerosis and Inflammatory Myopathy
    Abstract Poster Presenter: Robert Fairchild, MD,PhD,RhMSUS – Stanford University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1589: Whole Skin Gene Expression Analysis Identifies Discrete Modules That Differentiate Antinuclear Antibody Subsets in Systemic Sclerosis
    Abstract Poster Presenter: Kristina Clark, MD, PhD, MRCP – University of Oxford
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1590: Milder ILD with Preserved Lung Function Significantly Contributes to Respiratory Caused Mortality in SSc
    Abstract Poster Presenter: Anna-Maria Hoffmann-Vold, MD;PhD (she/her/hers) – Oslo University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    10:30 AM – 12:30 PM Eastern Time
    1591: Domains and Outcome Measures for the Assessment of Digital Vasculopathy and Raynaud Phenomenon in Juvenile Systemic Sclerosis: A Systematic Review
    Abstract Poster Presenter: Simone Appenzeller, MD, PhD – Unicamp
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    1:00 PM – 2:30 PM Eastern Time
    17S57: Abstracts: Systemic Sclerosis & Related Disorders – Clinical I
    Location: Room 147AB
    Abstract Moderator: Andreea Bujor, MD, PhD – Boston University
    Abstract Moderator: Jessica Gordon, MD,MSc (she/her/hers) – Hospital for Special Surgery
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Sunday, Nov 17th
    1:00 PM – 1:15 PM Eastern Time
    1689: Pulmonary Function Test Reference Equations May Drive Inequitable Classification of Restrictive Lung Disease Severity in Systemic Sclerosis
    Location: Room 147AB
    Presenting Author: Kamini Kuchinad, MD;MPH – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    1:15 PM – 1:30 PM Eastern Time
    1690: FAPI-PET/CT as a Predictor of Accelerated Lung Function Deterioration in Systemic Sclerosis Related Interstitial Lung Disease (ILD): Preliminary-interim Analysis from a Confirmatory Risk Factor Study
    Location: Room 147AB
    Presenting Author: Christina Bergmann, MD (she/her/hers) – Department Internal Medicine III, Friedrich-Alexander-University (FAU) Erlangen-Nurnber
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    1:30 PM – 1:45 PM Eastern Time
    1691: Treatment Response Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease
    Location: Room 147AB
    Presenting Author: Elizabeth Volkmann, MD,MS – University of California, Los Angeles
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    1:45 PM – 2:00 PM Eastern Time
    1692: Single Cell RNA-seq Identifies Circulating Double-negative-2 B-cell Population Associated with Progressive Scleroderma Interstitial Lung Disease
    Location: Room 147AB
    Presenting Author: Trinitee Oliver, BS – Cedars-Sinai Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    2:00 PM – 2:15 PM Eastern Time
    1693: Change in Forced Vital Capacity at Week 12 or 24 Has Prognostic Value for Outcome at Week 52 in Patients with Autoimmune Disease-Related Interstitial Lung Diseases
    Location: Room 147AB
    Presenting Author: Anna-Maria Hoffmann-Vold, MD;PhD (she/her/hers) – Oslo University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    2:15 PM – 2:30 PM Eastern Time
    1694: One-Year Survival Following Single versus Double Lung Transplantation in Adults with Systemic Autoimmune Rheumatic Disease-related Interstitial Lung Disease: A Nationwide Cohort Study
    Location: Room 147AB
    Presenting Author: Harry Hurley, MD, PhD (he/him/his) – Albert Einstein College of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    2:15 PM – 3:15 PM Eastern Time
    17S39: State of the Art Lecture: Precision Medicine in Systemic Sclerosis
    Location: Ballroom A
    Moderator: Tracy Frech, MD,MS – Vanderbilt University Medical Center
    Moderator: Monique Hinchcliff, MD;MS – Yale School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Sunday, Nov 17th
    2:15 PM – 2:45 PM Eastern Time
    Molecular Phenotypes of Systemic Sclerosis: Data-driven Approaches to Managing Clinical Manifestations of Systemic Sclerosis
    Location: Ballroom A
    Speaker: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    2:45 PM – 3:15 PM Eastern Time
    Functional Response Biomarkers for SSc-ILD: Using Molecular Imaging and Other Biomarkers to Guide Treatment Decisions
    Location: Ballroom A
    Speaker: Elizabeth Volkmann, MD,MS – University of California, Los Angeles
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    3:30 PM – 4:30 PM Eastern Time
    17S45: Great Debate: MCTD: Is It Just Letters?
    Location: Hall D/E
    Moderator: Jason Lee, MD,PhD,FRCPC – University of Calgary
    Moderator: Laura Cappelli, MD – Johns Hopkins School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Sunday, Nov 17th
    3:30 PM – 3:45 PM Eastern Time
    MCTD Is a Unique Rheumatic Disease
    Location: Hall D/E
    Interactive Speaker: Lisa Christopher-Stine, MD, MPH – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    3:45 PM – 4:00 PM Eastern Time
    MCTD Is Not a Unique Rheumatic Disease
    Location: Hall D/E
    Interactive Speaker: Peter Izmirly, MD – New York University Grossman School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    4:00 PM – 4:10 PM Eastern Time
    MCTD Is a Unique Rheumatic Disease - Rebuttal
    Location: Hall D/E
    Interactive Speaker: Oliver Distler, MD – Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    4:10 PM – 4:20 PM Eastern Time
    MCTD Is Not a Unique Rheumatic Disease - Rebuttal
    Location: Hall D/E
    Interactive Speaker: Judith James, MD,PhD – Oklahoma Medical Research Foundation
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Sunday, Nov 17th
    4:20 PM – 4:30 PM Eastern Time
    Great Debate: Q & A
    Location: Hall D/E
    Panelist: Lisa Christopher-Stine, MD, MPH – Johns Hopkins University
    Panelist: Peter Izmirly, MD – New York University Grossman School of Medicine
    Panelist: Oliver Distler, MD – Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland
    Panelist: Judith James, MD,PhD – Oklahoma Medical Research Foundation
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    7:30 AM – 8:30 AM Eastern Time
    MTP16A: Meet the Professor: IgG4-Related Disease
    Location: Room 155
    Seminar Presenter: John Stone, MD,MPH – Massachusetts General Hospital , Harvard Medical School
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Monday, Nov 18th
    7:30 AM – 8:30 AM Eastern Time
    MTP19A: Meet the Professor: Systemic Sclerosis
    Location: Room 153
    Seminar Presenter: Janet Pope, MD;FRCPC;MPH – University of Western Ontario
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Monday, Nov 18th
    9:00 AM – 10:30 AM Eastern Time
    18M11: Optimizing the Management of Skin Disease in Systemic Sclerosis: Using Clinical Features and Novel Disease Activity Measures to Guide Treatment Decisions
    Location: Room 150AB
    Moderator: Arissa Young, MD – UCLA
    Moderator: Rachel Wallwork, MD, MHS (she/her/hers) – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1.5 hours
  • Monday, Nov 18th
    9:00 AM – 9:30 AM Eastern Time
    Skin Treatment in Scleroderma: Using Clinical Data to Optimize Treatment Decisions
    Location: Room 150AB
    Speaker: Robyn Domsic – University of Pittsburgh
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    9:30 AM – 10:00 AM Eastern Time
    Can Novel Diagnostics Inform Early Intervention Decisions for Preventing Skin Fibrosis?
    Location: Room 150AB
    Speaker: Madelon Vonk, MD;PhD (she/her/hers) – Radboud University Nijmegen Medical Centre
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:00 AM – 10:30 AM Eastern Time
    Autologous Stem Cell Transplantation for Skin Involvement in SSc
    Location: Room 150AB
    Speaker: Ankoor Shah, MD – Duke University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    Systemic Sclerosis & Related Disorders – Basic Science Poster II
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    Systemic Sclerosis & Related Disorders – Clinical Poster III
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1814: Understanding Monocyte Derived Macrophages in the Skin of SSc Patients Through Single Cell Analysis of Blister Fluid Immune Cell Populations
    Abstract Poster Presenter: Sandra Lopez Garces, BSc,MSc – University College London
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1815: Leveraging Novel Systemic Sclerosis Disease Signatures to Build a Humanized Drug Discovery Funnel
    Abstract Poster Presenter: Lauren Reinke-Breen, PhD – AbbVie
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1816: Paracrine WNT Signaling Drives Pro-fibrotic Metabolic Activation of Systemic Sclerosis Macrophages
    Abstract Poster Presenter: Emily Morris, PhD – Dartmouth College
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1817: Activated Macrophages Mediate Loss of Dermal White Adipose Tissue in Fibrotic Skin
    Abstract Poster Presenter: Chanhyuk Park, BA – Geisel School of Medicine at Dartmouth
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1818: Distribution and Morphological Changes of Adventitial Fibroblasts in Healthy and Scleroderma Skin
    Abstract Poster Presenter: Banafsheh Nazari, MD, MSc (she/her/hers) – UPMC-Mercy
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1819: Insulin-like Growth Factor Binding Protein-7 (IGFBP7) Plays a Pathogenic Role in Dermal Fibrosis and Is Increased in Systemic Sclerosis
    Abstract Poster Presenter: Gayathri Guru Murthy, MS (she/her/hers) – University of Rochester Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1820: Disruption of Ca2+ Homeostasis and Enhanced Ca2+ Signaling in Scleroderma Fibroblasts Is Due to the Vicious Cycle Formed by Mitochondrial-derived Reactive Oxygen Species, CaMKII, and ER Extrusion Pump RYR2
    Abstract Poster Presenter: Yuzo Ikari, MD, PhD – Division of Rheumatology, Department of Internal Medicine, University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1821: Single-Cell RNA SequencingBioinformatic Pipeline Optimized for Non-Coding GenesIdentified LINC01503 and MIR193-BHG as Potential Pathogenic Effectors in Systemic Sclerosis Fibroblasts
    Abstract Poster Presenter: Sophie Wagner, BSc – University of Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1822: Analysis of Differential Activation of Lysophosphatidic Acid Regulated Genes in Diffuse and Limited Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: Medha Kanitkar, MD, MRCP – Royal Free Hospital, London UK
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1823: Identification and Prediction of Systemic Sclerosis Intrinsic Subtypes Using Semi-Supervised and Supervised Learning on Gene Expression Data of Multiple Cohorts
    Abstract Poster Presenter: Zhiyun Gong, MS, BSc – Dartmouth College
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1824: Skin Macrophage Subtypes and Impact of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis: Results from Single-cell Analyses of an Observational Data Set and a Phase I/II Randomized Controlled Trial
    Abstract Poster Presenter: Alain Lescoat, MD, PhD – CHU Rennes - University Rennes
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1825: Proteomic and Transcriptomic Analysis Reveal Elevated Senescent Signature in Systemic Sclerosis Fibrosis
    Abstract Poster Presenter: Poulami Dey, PhD – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1826: Unveiling the Primary Cilia Signature Driving Systemic Sclerosis Pathogenesis
    Abstract Poster Presenter: Maria Teves, DrPH – Virginia Commonwealth University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1827: Characterization of Fibroblast Subpopulations and Their Cellular Local Environments in Systemic Sclerosis Using Imaging Mass Cytometry
    Abstract Poster Presenter: Yi-Nan Li, PhD – University Hospital of Düsseldorf
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1828: SSc Fibroblasts Trigger a Systemic Type I Interferon Response in SSc Patients Through Canonical TGF-β Receptor Signalling
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1829: Genomic Analysis of Skin Biopsies Differentiates Major Anti-Nuclear Autoantibody Subsets in Limited Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: Philip Yee, MD – UCL
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1830: Single-cell RNA Sequencing Profiling of Very Early-Stage Systemic Sclerosis Skin Reveals a Fibroblast Pro-inflammatory Gene Signature and Keratinocyte Dysregulation
    Abstract Poster Presenter: Lumeng Li, MSc – Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1831: Role of Long Non-Coding RNA H19 in Mediating Skin Fibrosis in Systemic Sclerosis
    Abstract Poster Presenter: Begona Caballero-Ruiz, PhD – Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1832: Targeting Hippo Pathway Diminishes Disease Signaling in Scleroderma Skin
    Abstract Poster Presenter: Olesya Plazyo, PhD (she/her/hers) – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1833: Immune Complexes of Antibodies Directed to Angiotensin Receptor type-1 and Extracellular Vesicles Are Unique Modulators Contributing to Systemic Sclerosis
    Abstract Poster Presenter: Alexander Maximilian Hackel, PhD (he/him/his) – Department of Rheumatology and Clinical Immunology, University of Lübeck
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    1834: Altered Mechanotransduction via Myosin II Contributes to Collagen and IL-6 Production in Systemic Sclerosis Skin
    Abstract Poster Presenter: Barbara Russo, n/a (she/her/hers) – Hopitaux Universitaire de Geneva
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2441: Investigating Kidney Disease Risks in Systemic Sclerosis (SSc) – Effects of Proton Pump Inhibitors (PPI): Retrospective Analysis
    Abstract Poster Presenter: Irakli Tskhakaia, MD (he/him/his) – Jefferson Einstein Philadelphia Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2442: Clustering Algorithm as an Exploratory Analysis of Different Clinical Phenotypes in Systemic Sclerosis. Data from the PRECISESADS Study
    Abstract Poster Presenter: Santiago Dans Caballero, -None- – H. U. Reina Sofía
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2443: The Clinical Phenotype of Anti-Th/To+ Patients in Systemic Sclerosis: A Case-control Study Within the European Scleroderma Trials and Research (EUSTAR) Cohort
    Abstract Poster Presenter: Liala Moschetti, MD (she/her/hers) – Rheumatology Unit ASST Spedali Civili and University of Brescia
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2444: Performance of the DETECT Algorithm and Cluster Analysis in Screening for Systemic Sclerosis Pulmonary Hypertension Groups
    Abstract Poster Presenter: Ryan Osgueritchian, MD – Johns Hopkins University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2445: Effects of Aminaphtone on TGF-beta1 Serum Concentration as Concomitant Treatment to Standard Therapy in Systemic Sclerosis Patients: A Pilot Study
    Abstract Poster Presenter: Alberto Sulli, MD – Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2446: Nailfold Videocapillaroscopy Findings in Patients with Limited Cutaneous versus Diffuse Cutaneous Systemic Sclerosis: The First Detailed Retrospective Study
    Abstract Poster Presenter: Alberto Sulli, MD – Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2447: Features of Anti-Fibrillarin Positive Systemic Sclerosis Patients and Ethnic Differences: A European Multicenter Cohort
    Abstract Poster Presenter: Roberto D'Alessandro, MD – APHP
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2448: Content Validity and Sensitivity to Change of ScleroID Through the Natural History of Scleroderma. a Validated Tool to Measure the Impact of SSc on How Patients Feel and Function
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2449: Acid Reflux Triggers Type I Interferon and Persistent Epithelial-mesenchymal Transition in Esophageal Epithelial Cells. a Novel Microenvironment Contribution to the Pathogenesis of Systemic Sclerosis
    Abstract Poster Presenter: Safoura Zahed Mohajerani, PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2450: Disease Progression in Anti-Centromere Positive Systemic Sclerosis Patients
    Abstract Poster Presenter: Jeska de Vries-Bouwstra, MD;PhD – Leiden University Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2451: Prognostic Value of Functional Outcomes in a Italian Multicentric Cohort of Early SSc-ILD Patients
    Abstract Poster Presenter: Lorenzo Beretta, MD – Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2452: Multimodal Ultrasound in the Assessment of Sarcopenia-related Muscle Involvement in Patients with Systemic Sclerosis: A Multicentric Study
    Abstract Poster Presenter: Riccardo Bixio, MD (he/him/his) – University of Verona
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2453: Gastrointestinal Symptom Severity and Intestinal Permeability in Systemic Sclerosis: A Single Center Prospective Study
    Abstract Poster Presenter: Ashima Makol, MD (she/her/hers) – Mayo Clinic, Rochester, MN
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2454: Age-Adjusted Mortality Rate Trends in Systemic Sclerosis in the United States from 1999 to 2020
    Abstract Poster Presenter: Ansaam Daoud, MD – Case Western Reserve University/University Hospitals
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2455: Improvement Across Multi-organ Domains and Patient Reported Outcomes in Refractory Juvenile-Onset Systemic Sclerosis (jSSc) up to 4 Years After Autologous Stem Cell Transplantation (ASCT)
    Abstract Poster Presenter: Jonathan Li, MD – Division of Rheumatology, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2456: High Levels of Circulating IFNα Are Associated with Increased Mortality in Patients with Diffuse Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: François Maillet, UPC – AP HP
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2457: Polypharmacy, Drug-drug Interactions, and Adverse Drug Reactions Among Systemic Sclerosis Patients: A Cross-sectional Risk Factor Study
    Abstract Poster Presenter: Benjamin Chaigne, MD, PhD – Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP)
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2458: Risk Factors for Progression of Interstitial Lung Disease in Patients with Early Diffuse Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: Julie Urgiles, MD – Columbia University Irving Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2459: Use of Nailfold Capillaroscopy as a Predictor of Cardiovascular Events and Mortality in Systemic Sclerosis
    Abstract Poster Presenter: Carlos Valera Ribera, MD (he/him/his) – Hospital Universitario Doctor Peset
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2460: Severe Gastrointestinal Involvement in Systemic Sclerosis: A New “Transversal” Subset of Disease to Be Prioritised for Intervention Trials
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2461: Prevalence and Impact of Peripheral Neuropathy in SSc: A Frequent and Disabling Manifestation in SSc, and a Potential Surrogate Marker for Autonomic Neuropathy
    Abstract Poster Presenter: Begonya Alcacer-Pitarch, PhD, BSc (she/her/hers) – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2462: A Potent Inhibitor of PAI-1, MDI-2517, Mitigates Disease Severity in Preclinical Models of Systemic Sclerosis
    Abstract Poster Presenter: Enming Su, PhD – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2463: Interstitial Lung Disease in Very Early Systemic Sclerosis – a Clinical and Radiological Characterization
    Abstract Poster Presenter: Sinziana Muraru, MD – University of Zurich, University Hospital Zurich
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2464: Thymic Size Longitudinal Changes on Chest High-resolution Computed Tomography After Autologous Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis
    Abstract Poster Presenter: Gregory Pugnet, MD;PhD – Toulouse Rangueil University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2465: Subclinical Loss of Lung Volumes in Very Early SSc: Evidence from Two Independent Cohorts in EUSTAR
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2466: Ranked Composite Important Difference (RCID) Scores in Patients with Diffuse Cutaneous Systemic Sclerosis and Interstitial Lung Disease
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2467: Elderly Systemic Sclerosis. Clinical Presentation and Outcome
    Abstract Poster Presenter: Miriam Retuerto Guerrero, MD (she/her/hers) – Complejo Asistencial Universitario de León
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2468: Audio-Guided Imagery Positively Impacted Patients with Raynaud's Phenomenon Associated Connective Tissue Disease
    Abstract Poster Presenter: Cristina Padilla, MD, MS (she/her/hers) – University of Pittsburgh Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2469: Machine Learning Identifies Oesophageal Symptoms as a New Red Flag for for Very Early Diagnosis of Systemic Sclerosis (VEDOSS): A EUSTAR Analysis
    Abstract Poster Presenter: Francesco Del Galdo, MD,PhD – University of Leeds
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2470: Progression Patterns in Systemic Sclerosis - Associated Interstitial Lung Diseases
    Abstract Poster Presenter: Anais Roeser, MD (she/her/hers) – Université Paris Cité
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2471: Association of Telangiectasias with Autoantibodies and Clinical Manifestations in Systemic Sclerosis
    Abstract Poster Presenter: Namitha Nair, MBBS – University of Pittsburgh Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2472: Are Anti-centromere Antibodies (aCENP) Predictive of Systemic Sclerosis Development in Patients Without Raynaud´s Phenomenon?
    Abstract Poster Presenter: Olga Sanchez Pernaute, MD,PhD – Fundacion Jimenez Diaz Univ. Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2473: Criterion Validity of Modified Rodnan Skin Score: Does It Capture Skin Thickness or Hardening? Results of a Large Skin Histology Study
    Abstract Poster Presenter: Shervin Assassi, MD, MS – UTHealth Houston Division of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2474: High-throughput Screening Identifies Specific Molecular Markers for ILD in Patients with Rheumatic Diseases
    Abstract Poster Presenter: Anna-Maria Hoffmann-Vold, MD;PhD (she/her/hers) – Oslo University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2475: The Critical Role of Annual HRCT in Identifying ILD Progression and Assessing Outcome in SSc
    Abstract Poster Presenter: Anna-Maria Hoffmann-Vold, MD;PhD (she/her/hers) – Oslo University Hospital
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2476: The Impact of Systemic Sclerosis Manifestations on Survival and Humanistic Burden: A Targeted Literature Review
    Abstract Poster Presenter: Elizabeth Volkmann, MD,MS – University of California, Los Angeles
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    10:30 AM – 12:30 PM Eastern Time
    2477: Quantifying Tissue Microstructural Changes in Scleroderma Skin Using a Novel, Point-of-care, High-frequency-ultrasound Instrument
    Abstract Poster Presenter: Kimberly S. Lakin, MD, MS – Hospital for Special Surgery
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    11:30 AM – 12:30 PM Eastern Time
    MTP16B: Meet the Professor: IgG4-Related Disease
    Location: Room 155
    Seminar Presenter: John Stone, MD,MPH – Massachusetts General Hospital , Harvard Medical School
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Monday, Nov 18th
    11:30 AM – 12:30 PM Eastern Time
    MTP19B: Meet the Professor: Systemic Sclerosis
    Location: Room 153
    Seminar Presenter: Janet Pope, MD;FRCPC;MPH – University of Western Ontario
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Monday, Nov 18th
    1:00 PM – 2:30 PM Eastern Time
    18M34: Gasping for Cellular Repair: New Insights Into Interstitial Lung Disease Pathogenesis and Treatment
    Location: Room 143ABC
    Moderator: Elana Bernstein, MD;MSc – Division of Rheumatology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center
    Moderator: Monica Yang, MD – UCSF
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1.5 hours
  • Monday, Nov 18th
    1:00 PM – 1:30 PM Eastern Time
    New Insights into Biomarkers and Biology of Systemic Sclerosis-ILD
    Location: Room 143ABC
    Speaker: Shervin Assassi, MD, MS – UTHealth Houston Division of Rheumatology
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    1:30 PM – 2:00 PM Eastern Time
    Vascular-Parenchymal Crosstalk in ILD
    Location: Room 143ABC
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    2:00 PM – 2:30 PM Eastern Time
    Pipeline to Developing New ILD Therapies
    Location: Room 143ABC
    Speaker: Farida Ahangari, MD – Yale School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    2:15 PM – 3:15 PM Eastern Time
    18M38: CARE to Test Your Knowledge: Scleroderma Renal Crisis
    Location: Ballroom C
    Moderator: DeAnna Baker Frost, MD,PhD – Medical University of South Carolina
    Moderator: Virginia Steen, MD – Georgetown University School of Medicine
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 1 hours
  • Monday, Nov 18th
    2:15 PM – 3:15 PM Eastern Time
    CARE: Scleroderma Renal Crisis
    Location: Ballroom C
    Speaker: Christopher Denton, MD;PhD – University College London
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    3:00 PM – 4:30 PM Eastern Time
    18M70: Abstracts: Systemic Sclerosis & Related Disorders – Clinical II
    Location: Room 207AB
    Abstract Moderator: Shervin Assassi, MD, MS – UTHealth Houston Division of Rheumatology
    Abstract Moderator: Cristina Padilla, MD, MS (she/her/hers) – University of Pittsburgh Medical Center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Monday, Nov 18th
    3:00 PM – 3:15 PM Eastern Time
    2641: Identification of Systemic Sclerosis Intrinsic Subtypes in the ASSET Clinical Trial Using PBC Gene Expression
    Location: Room 207AB
    Presenting Author: Michael L. Whitfield, PhD – Geisel School of Medicine at Dartmouth
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    3:15 PM – 3:30 PM Eastern Time
    2642: Identifying Systemic Sclerosis Molecular Subtypes by Their Cellular Signature – Deconvoluting the Puzzle
    Location: Room 207AB
    Presenting Author: Doron Rimar, MD (he/him/his) – Bnai Zion medical center
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    3:30 PM – 3:45 PM Eastern Time
    2643: Integrated Bulk and Single Cell RNA Sequencing Defines Key Pathways Regulating Myofibroblast Differentiation Across ANA Subgroups in Diffuse Systemic Sclerosis
    Location: Room 207AB
    Presenting Author: Kristina Clark, MD, PhD, MRCP – University of Oxford
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    3:45 PM – 4:00 PM Eastern Time
    2644: Baseline Fibroblast Immunophenotype Predicts Clinical Improvement Among Individuals with Early Diffuse Cutaneous Systemic Sclerosis
    Location: Room 207AB
    Presenting Author: Kimberly S. Lakin, MD, MS – Hospital for Special Surgery
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    4:00 PM – 4:15 PM Eastern Time
    2645: Human NCF1-p.R90H Variant Promotes Pulmonary Fibrosis in the Bleomycin-induced Mouse Model and Systemic Sclerosis Patients via Expansion of SPP1+Monocytes-derived Macrophages
    Location: Room 207AB
    Presenting Author: Xinran Yuan, MD, PhD – Medical University of South Carolina/Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Monday, Nov 18th
    4:15 PM – 4:30 PM Eastern Time
    2646: Rare Variants in the IL1RAP Gene Implicate the IL-1 Signaling Pathway in the Pathogenesis of Systemic Sclerosis in African and European Ancestries
    Location: Room 207AB
    Presenting Author: Yosuke Kunishita, MD, PhD – Scleroderma Genomics and Health Disparities Unit, NIAMS, NIH
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    11:00 AM – 12:30 PM Eastern Time
    19T16: Abstracts: Systemic Sclerosis & Related Disorders – Clinical III
    Location: Room 102AB
    Abstract Moderator: Lorinda Chung, MD, MS – Stanford University
    Abstract Moderator: Antonia Valenzuela, MD,MS – Pontificia Universidad Catolica de Chile
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
     CME 0 hours
  • Tuesday, Nov 19th
    11:00 AM – 11:15 AM Eastern Time
    2683: Optical Coherence Angiography: A Non-invasive, Safe Method for Assessing the Systemic Sclerosis Related Vasculopathy Beyond Nailfold Capillaries
    Location: Room 102AB
    Presenting Author: Pavel Nikitin, MD – University of Houston
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    11:15 AM – 11:30 AM Eastern Time
    2684: Assessment of Skin in Patients with Systemic Sclerosis Using High Frequency Ultrasound : A Comparative Study with Histology and Clinical Parameters of Skin Disease
    Location: Room 102AB
    Presenting Author: Ruhani Desai, MD – EVMS
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    11:30 AM – 11:45 AM Eastern Time
    2685: Association Between Gastrointestinal Bacterial Species and Radiological Features of Systemic Sclerosis-Interstitial Lung Disease (SSc-ILD): A Multicenter Study from the SSc Microbiome Consortium Project
    Location: Room 102AB
    Presenting Author: Arissa Young, MD – UCLA
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    11:45 AM – 12:00 PM Eastern Time
    2686: Dose Escalation Safety Study of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis:Clinical Results and Mechanistic Analysis of Skin and Peripheral Blood Mononuclear Cells
    Location: Room 102AB
    Presenting Author: David Fox, MD – University of Michigan
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    12:00 PM – 12:15 PM Eastern Time
    2687: Therapeutic Choices in Systemic Sclerosis Associated Interstitial Lung Disease, a Survey of International Experts
    Location: Room 102AB
    Presenting Author: Iazsmin Bauer Ventura, MD, MS – University of Chicago
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)
  • Tuesday, Nov 19th
    12:15 PM – 12:30 PM Eastern Time
    2688: HLA-DRB4: A Novel Susceptibility Locus in Systemic Sclerosis Patients with Severe Calcinosis
    Location: Room 102AB
    Fibrosing rheumatic diseases (scleroderma, MCTD, IgG4-related disease, scleroderma mimics)